Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans

IntroductionVascular dysfunction and chronic inflammation are characteristics of obesity-induced adipose tissue dysfunction. Proinflammatory cytokines can drive an endothelial-to-mesenchymal transition (EndoMT), where endothelial cells undergo a phenotypic switch to mesenchymal-like cells that are p...

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Hlavní autoři:	Nicholas W. Chavkin, Tanvi Vippa, Changhee Jung, Stephanie McDonnell, Karen K. Hirschi, Noyan Gokce, Kenneth Walsh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-09-01
Edice:	Frontiers in Cardiovascular Medicine
Témata:	endothelial-to-mesenchymal transition obesity adipose endothelium aging vascular biology
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1264479/full
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