Safety and effectiveness of the early-onset sepsis calculator to reduce antibiotic exposure in at-risk newborns: a cluster-randomised controlled trialResearch in context

Summary: Background: Newborns are at risk for early-onset sepsis (EOS), occurring 0.2–2.0 per 1000 live births, and for antibiotic overtreatment: approximately 5–15% receive antibiotics for suspected EOS under conventional guidelines with categorical risk factor assessment. Use of the multivariate...

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Главные авторы:	Bo M. van der Weijden, Sanne W.C.M. Janssen, Marijke C. van der Weide, Renske J.P.M. Cornelisse-van Vugt, Gavin W. ten Tusscher, Claire A.M. Lutterman, Arvid W.A. Kamps, Carmen M. Lorente Flores, Jeroen Hol, Henriëtte van Laerhoven, Maarten Rijpert, Nadia A. Oeij, Irene A.M. Schiering, Sylvia A. Obermann-Borst, Douwe H. Visser, Lisanne M. van Leeuwen, René F. Kornelisse, Annemarie M.C. van Rossum, Merijn W. Bijlsma, Frans B. Plötz, Niek B. Achten
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-09-01
Серии:	EClinicalMedicine
Предметы:	Early-onset sepsis calculator Early-onset sepsis EOS Neonatal sepsis calculator
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2589537025003517
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