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Synthesis of new Conjugates of some NSAIDs with Sulfonamide as Possible Mutual Prodrugs using Tyrosine Spacer for Colon Targeted Drug Delivery

The purpose of this research work is to synthesize conjugates of some NSAIDs with sulfamethoxazole as possible mutual prodrugs to overcome the local gastric irritation of NSAID with free carboxyl group by formation of ester linkage that supposed to remain intact in stomach and may hydrolyze in intes...

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Detalhes bibliográficos
Principais autores: Shayma L. Abdulhadi, Ahlam J. Qasir, Nadeem A. Abdul Razzak
Formato: Artigo
Idioma:Inglês
Publicado em: College of Pharmacy University of Baghdad 2017-02-01
coleção:Iraqi Journal of Pharmaceutical Sciences
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Acesso em linha:https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/115
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