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Overexpression of thioredoxin in islets transduced by a lentiviral vector prolongs graft survival in autoimmune diabetic NOD mice

<p>Abstract</p> <p>Pancreatic islet transplantation is considered an appropriate treatment to achieve insulin independence in type I diabetic patients. However, islet isolation and transplantation-induced oxidative stress and autoimmune-mediated destruction are still the major obstacles to the long-...

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Bibliografiske detaljer
Principais autores: Sytwu Huey-Kang, Chou Feng-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2009-08-01
Serier:Journal of Biomedical Science
Online adgang:http://www.jbiomedsci.com/content/16/1/71
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