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Case Report: TPR-ALK fusion-positive inflammatory myofibroblastic tumour treated with sequential ALK inhibitors

BackgroundInflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm, frequently driven by oncogenic kinase fusions, most commonly involving anaplastic lymphoma kinase (ALK). Standard cytotoxic therapies have limited efficacy in unresectable IMT. ALK inhibitors such as crizotinib are r...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Fabiano Flauto, Filippo Vitale, Caterina De Luca, Rosa Maria Di Crescenzo, Francesco Petteruti, Annarita Peddio, Giuseppe Neola, Vincenzo Damiano
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2026-03-01
Rangatū:Frontiers in Oncology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fonc.2026.1778283/full
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