The first-line antituberculosis drugs, and their fixed-dose combination induced abnormal sperm morphology and histological lesions in the testicular cells of male mice

Rifampicin (RIF), Isoniazid (INH), Ethambutol (EMB), Pyrazinamide (PZA), and/or their fixed-dose combination (FDC) are extensively prescribed in the cure of Tuberculosis (TB) globally. In spite of the beneficial effect, these drugs are capable of inducing cellular toxicity. Existing information on t...

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Principais autores:	Adekunle A. Bakare, Victoria Y. Moses, Charles T. Beckely, Toluwani I. Oluyemi, Gift O. Ogunfeitimi, Aduragbemi A. Adelaja, Glory T. Ayorinde, Adeyinka M. Gbadebo, Olukunle S. Fagbenro, Olusegun I. Ogunsuyi, Opeoluwa M. Ogunsuyi, Olusoji Mayowa Ige
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2022-12-01
סדרה:	Frontiers in Cell and Developmental Biology
נושאים:	first-line antituberculosis drug DNA damage ethambutol isoniazid rifampicin pyrazinamide
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fcell.2022.1023413/full
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