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Quantifying the molecular origins of opposite solvent effects on protein-protein interactions.

Although the nature of solvent-protein interactions is generally weak and non-specific, addition of cosolvents such as denaturants and osmolytes strengthens protein-protein interactions for some proteins, whereas it weakens protein-protein interactions for others. This is exemplified by the puzzling...

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Detaylı Bibliyografya
Asıl Yazarlar: Vincent Vagenende, Alvin X Han, Han B Pek, Bernard L W Loo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2013-01-01
Seri Bilgileri:PLoS Computational Biology
Online Erişim:http://europepmc.org/articles/PMC3656110?pdf=render
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