Hippocampal exosomes from stroke aggravate post-stroke depression by regulating the expression of proBDNF and p75NTR and altering spine density

Abstract Post-stroke depression (PSD) affects millions of patients who suffer cerebral stroke. However, the molecular mechanisms and pathophysiology are poorly understood. Previous studies have shown that exosomes have been proven to be involved in neuropsychiatric disorders such as stroke and post-...

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Κύριοι συγγραφείς:	Sheng Huang, Ying Nie, Jun Qin, Meiling Wen, Qingru Wang, Fan Xie, Fanxiu Song, Bangkun Yang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2024-11-01
Σειρά:	Scientific Reports
Θέματα:	Post-stroke depression Hippocampal exosomes proBDNF p75NTR Synaptotagmin PSD95
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-024-79558-x
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