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The Effect of a New <i>N</i>-hetero Cycle Derivative on Behavior and Inflammation against the Background of Ischemic Stroke

Ischemic stroke triggers a whole cascade of pathological changes in the brain, one of which is postischemic inflammation. Since in such cases thrombolytic therapy is often not possible, methods that modulate inflammation and affect microglia become particularly interesting. We synthesized 3-(2-oxo-4...

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Principais autores: Denis A. Borozdenko, Tatiana A. Shmigol, Aiarpi A. Ezdoglian, Darya I. Gonchar, Natalia. Y. Karpechenko, Dmitri N. Lyakhmun, Anastasia D. Shagina, Elvira A. Cherkashova, Daria D. Namestnikova, Ilya L. Gubskiy, Anastasia A. Chernysheva, Nina M. Kiseleva, Vadim V. Negrebetsky, Yuri I. Baukov
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-08-01
Serier:Molecules
Fag:
neuroprotective activity
inflammation
transient MCAO
experimental ischemic stroke
behavioral tests
Online adgang:https://www.mdpi.com/1420-3049/27/17/5488
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