Direct carbapenemase typing from disc diffusion antibiograms with MALCA (MAchine Learning CArbapenemase)

Abstract Carbapenemase-producing Enterobacterales (CPE) present limited therapeutic options. Optimal treatment requires identifying the carbapenemase type, often requiring confirmatory testing beyond routine susceptibility results. We develop MALCA, a machine-learning classifier that uses routine di...

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Autori principali:	Cécile Emeraud, Yahia Benzerara, Hippolyte De Swardt, Alexandra Aubry, Nicolas Veziris, Agnès B. Jousset, Inès Rezzoug, Léna Latour, Alice Pages, Sarah Ronsin, Corentin Poignon, Rémy A. Bonnin, Mariette Matondo, Quentin Giai Gianetto, Laurent Dortet, Alexandre Godmer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-05-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-026-72713-0
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Direct carbapenemase typing from disc diffusion antibiograms with MALCA (MAchine Learning CArbapenemase)

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