CD39 expression by regulatory T cells participates in CD8+ T cell suppression during experimental Trypanosoma cruzi infection.

An imbalance between suppressor and effector immune responses may preclude cure in chronic parasitic diseases. In the case of Trypanosoma cruzi infection, specialized regulatory Foxp3+ T (Treg) cells suppress protective type-1 effector responses. Herein, we investigated the kinetics and underlying m...

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Autors principals:	Cintia L Araujo Furlan, Santiago Boccardo, Constanza Rodriguez, Verónica S Mary, Camila M S Gimenez, Simon C Robson, Adriana Gruppi, Carolina L Montes, Eva V Acosta Rodríguez
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2024-04-01
Col·lecció:	PLoS Pathogens
Accés en línia:	https://doi.org/10.1371/journal.ppat.1012191
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