Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function

Natural killer (NK) cells are innate lymphocytes that play a pivotal role in the immune surveillance and elimination of transformed or virally infected cells. Using a chemo-genetic approach, we identify BET bromodomain containing proteins BRD2 and BRD4 as central regulators of NK cell functions, inc...

Descripció completa

Dades bibliogràfiques

Autors principals:	Adam P. Cribbs, Panagis Filippakopoulos, Martin Philpott, Graham Wells, Henry Penn, Henrik Oerum, Viia Valge-Archer, Marc Feldmann, Udo Oppermann
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	BET bromodomain BRD2 BRD4 NK cell epigenetics (DNA methylation histone modifications)
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.626255/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!