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Synthesis and Cytotoxic Evaluation of a Series of 2-Amino-Naphthoquinones against Human Cancer Cells

The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 (ovarian), NCI-H358M (bronchoalveolar lung carcinom...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Thiago A. P. de Moraes, Maria J. S. Filha, Celso A. Camara, Tania M. S. Silva, Bruno M. Soares, Igor S. Bomfim, Claudia Pessoa, George C. Ximenes, Valdemiro A. Silva
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2014-08-01
Schriftenreihe:Molecules
Schlagworte:
naphthoquinones
aminoacid naphthoquinones
cytotoxicity
cancer cells
Online-Zugang:http://www.mdpi.com/1420-3049/19/9/13188
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