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Molecular genetics, therapeutics and RET inhibitor resistance for medullary thyroid carcinoma and future perspectives

Abstract Medullary thyroid carcinoma (MTC) is a rare type of thyroid malignancy that accounts for approximately 1–2% of all thyroid cancers (TCs). MTC include hereditary and sporadic cases, the former derived from a germline mutation of rearrangement during transfection (RET) proto-oncogene, whereas...

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Главные авторы: Ying Zhang, Wei-Hui Zheng, Shi-Hong Zhou, Jia-Lei Gu, Qing Yu, Yi-Zhou Zhu, Yu-Jie Yan, Zhi Zhu, Jin-Biao Shang
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2024-09-01
Серии:Cell Communication and Signaling
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Online-ссылка:https://doi.org/10.1186/s12964-024-01837-x
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