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Comprehensive investigation of the molecular basis of cancer dependencies suggests therapeutic options for breast cancer

Objective: Large-scale CRISPR screens have identified essential genes across cancer cell lines, but links between tumor functional properties and specific dependencies require investigation to reveal the mechanisms underlying dependencies and broaden understanding of targeted therapy. Methods: We se...

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Главные авторы: Rui Ding, Zhiming Shao, Tianjian Yu
Формат: Artigo
Язык:Inglês
Опубликовано: China Anti-Cancer Association 2025-12-01
Серии:Cancer Biology & Medicine
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Online-ссылка:https://www.cancerbiomed.org/content/22/12/1605
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