T cell independent antibody responses with class switch and memory using peptides anchored on liposomes
Abstract Vaccines generally require T lymphocytes for B-cell activation and immunoglobulin class switching in response to peptide or protein antigens. In the absence of T cells, limited IgG class switch takes place, germinal centers are short-lived, and the B cells lack memory. Here, immunization of...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2024-06-01
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| Schriftenreihe: | npj Vaccines |
| Online-Zugang: | https://doi.org/10.1038/s41541-024-00902-3 |
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