Transcriptomic landscape around wound bed defines regenerative versus non-regenerative outcomes in mouse digit amputation.

In the mouse distal terminal phalanx (P3), it remains mystery why amputation at less than 33% of the digit results in regeneration, while amputation exceeding 67% leads to non-regeneration. Unraveling the molecular mechanisms underlying this disparity could provide crucial insights for regenerative...

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Detalhes bibliográficos

Principais autores:	Archana Prabahar, Connie S Chamberlain, Ray Vanderby, William L Murphy, William Dangelo, Kulkarni Mangesh, Bryan Brown, Barsanjit Mazumder, Stephen Badylak, Peng Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2025-04-01
coleção:	PLoS Computational Biology
Acesso em linha:	https://doi.org/10.1371/journal.pcbi.1012997
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