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Dickkopf-1 (DKK1) blockade mitigates osteogenesis imperfecta (OI) related bone disease

Abstract Background The current treatment of osteogenesis imperfecta (OI) is imperfect. Our study thus delves into the potential of using Dickkopf-1 antisense (DKK1-AS) to treat OI. Methods We analysed serum DKK1 levels and their correlation with lumbar spine and hip T-scores in OI patients. Compara...

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Bibliografische gegevens
Hoofdauteurs: Jih-Yang Ko, Feng-Sheng Wang, Wei-Shiung Lian, Fu-Shine Yang, Jeng-Wei Chen, Po-Hua Huang, Chin-Yi Liao, Shu-Jui Kuo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2024-05-01
Reeks:Molecular Medicine
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Online toegang:https://doi.org/10.1186/s10020-024-00838-3
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