Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

Wnt5a-Ror signaling constitutes a developmental pathway crucial for embryonic tissue morphogenesis, reproduction and adult tissue regeneration, yet the molecular mechanisms by which the Wnt5a-Ror pathway mediates these processes are largely unknown. Using a proteomic screen, we identify the kinesin...

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Autors principals:	Michael W Susman, Edith P Karuna, Ryan C Kunz, Taranjit S Gujral, Andrea V Cantú, Shannon S Choi, Brigette Y Jong, Kyoko Okada, Michael K Scales, Jennie Hum, Linda S Hu, Marc W Kirschner, Ryuichi Nishinakamura, Soichiro Yamada, Diana J Laird, Li-En Jao, Steven P Gygi, Michael E Greenberg, Hsin-Yi Henry Ho
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2017-09-01
Col·lecció:	eLife
Matèries:	noncanonical Wnt signaling Ror signal transduction tissue morphogenesis regulated proteolysis Kif26b
Accés en línia:	https://elifesciences.org/articles/26509
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