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Hybridization and amplification rate correction for affymetrix SNP arrays

<p>Abstract</p> <p>Background</p> <p>Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation...

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Principais autores: Wang Quan, Peng Peichao, Qian Minping, Wan Lin, Deng Minghua
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2012-06-01
Series:BMC Medical Genomics
Assuntos:
SNP array
Copy number variation (CNV)
Cross-hybridization
Genomic waves
Acceso en liña:http://www.biomedcentral.com/1755-8794/5/24
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