Brain-derived neurotrophic factor/tropomyosin receptor kinase B signaling in spinal muscular atrophy and amyotrophic lateral sclerosis

Tropomyosin receptor kinase B (TrkB) and its primary ligand brain-derived neurotrophic factor (BDNF) are expressed in the neuromuscular system, where they affect neuronal survival, differentiation, and functions. Changes in BDNF levels and full-length TrkB (TrkB-FL) signaling have been revealed in s...

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Autori principali:	Chunchu Deng, Hong Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-01-01
Serie:	Neurobiology of Disease
Soggetti:	Spinal muscular atrophy Amyotrophic lateral sclerosis Brain-derived neurotrophic factor Tyrosine receptor kinase B Neuromuscular junction Motor function
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0969996123003935
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