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Mutations altering the interplay between GkDnaC helicase and DNA reveal an insight into helicase unwinding.

Replicative helicases are essential molecular machines that utilize energy derived from NTP hydrolysis to move along nucleic acids and to unwind double-stranded DNA (dsDNA). Our earlier crystal structure of the hexameric helicase from Geobacillus kaustophilus HTA426 (GkDnaC) in complex with single-s...

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Príomhchruthaitheoirí: Yu-Hua Lo, Shih-Wei Liu, Yuh-Ju Sun, Hung-Wen Li, Chwan-Deng Hsiao
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2011-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC3236778?pdf=render
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