Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo

Immunopathology in hepatitis B virus (HBV) infection is driven by innate and adaptive immunity. Whether the hepatitis B surface antigen (HBsAg) affects hepatic antiviral signalling was investigated in HBV-transgenic mouse models that either accumulate (Alb/HBs, Tg[Alb1HBV]Bri44), lack (Tg1.4HBV-s-mu...

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Bibliografische Detailangaben

Hauptverfasser:	Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Martin Trippler, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-05-01
Schriftenreihe:	Viruses
Schlagworte:	hepatitis B virus hepatitis B surface antigen immune evasion pattern recognition toll-like receptor
Online-Zugang:	https://www.mdpi.com/1999-4915/15/5/1203
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