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Eos negatively regulates human γ-globin gene transcription during erythroid differentiation.

BACKGROUND: Human globin gene expression is precisely regulated by a complicated network of transcription factors and chromatin modifying activities during development and erythropoiesis. Eos (Ikaros family zinc finger 4, IKZF4), a member of the zinc finger transcription factor Ikaros family, plays...

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Principais autores: Hai-Chuan Yu, Hua-Lu Zhao, Zhi-Kui Wu, Jun-Wu Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3145782?pdf=render
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