Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer

Abstract Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability after a paralyzing injury. Here, we find that ependymal cells in zebrafish spinal cords produce the neurogenic factor Hb-egfa upon transection injury. Animals with hb-egfa mutations display defective...

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Hlavní autoři:	Valentina Cigliola, Adam Shoffner, Nutishia Lee, Jianhong Ou, Trevor J. Gonzalez, Jiaul Hoque, Clayton J. Becker, Yanchao Han, Grace Shen, Timothy D. Faw, Muhammad M. Abd-El-Barr, Shyni Varghese, Aravind Asokan, Kenneth D. Poss
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2023-08-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-023-40486-5
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