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The 40Fp8 vaccine strain is safe and protects pregnant ewes from a virulent RVFV challenge

Abstract In the present study, we evaluated the immunogenicity, safety and protective efficacy of the attenuated RVFV-40Fp8 strain in natural hosts (non-pregnant ewes) and in a highly susceptible host infection model such as pregnant ewes in the first third of pregnancy. Our results confirm the immu...

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Autors principals: Belén Borrego, Celia Alonso, Sandra Moreno, Eva Calvo-Pinilla, Gema Lorenzo, Pedro J. Sánchez-Cordón, Alejandro Brun
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-08-01
Col·lecció:npj Vaccines
Accés en línia:https://doi.org/10.1038/s41541-025-01250-6
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