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Hypoxia increases persulfide and polysulfide formation by AMP kinase dependent cystathionine gamma lyase phosphorylation

Hydropersulfide and hydropolysulfide metabolites are increasingly important reactive sulfur species (RSS) regulating numerous cellular redox dependent functions. Intracellular production of these species is known to occur through RSS interactions or through translational mechanisms involving cystein...

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Main Authors: Shafiul Alam, Sibile Pardue, Xinggui Shen, John D. Glawe, Takashi Yagi, Mohammad Alfrad Nobel Bhuiyan, Rakesh P. Patel, Paari S. Dominic, Chiranjiv S. Virk, Md Shenuarin Bhuiyan, A. Wayne Orr, Chad Petit, Gopi K. Kolluru, Christopher G. Kevil
Format: Artigo
Language:Inglês
Published: Elsevier 2023-12-01
Series:Redox Biology
Subjects:
Cystathionine gamma lyase
Phosphorylation
Polysulfide
Persulfide
AMP kinase
Ischemia
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003506
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