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Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion

ABSTRACT Antibiotic resistance is rapidly spreading via the horizontal transfer of resistance genes in mobile genetic elements. While plasmids are key drivers of this process, few integrative phages encode antibiotic resistance genes. Here, we find that phage-plasmids, elements that are both phages...

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Principais autores: Eugen Pfeifer, Rémy A. Bonnin, Eduardo P. C. Rocha
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2022-10-01
סדרה:mBio
נושאים:
antibiotic resistance
bacteriophages
integrons
phage genomics
plasmids
prophage induction
גישה מקוונת:https://journals.asm.org/doi/10.1128/mbio.01851-22
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