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Non-cyp51A Azole-Resistant Aspergillus fumigatus Isolates with Mutation in HMG-CoA Reductase

The recent increase in azole-resistant Aspergillus fumigatus is a global concern. Identifying the mutations that confer azole resistance is essential for developing novel methods for prompt diagnosis and effective drug treatment. We screened A. fumigatus clinical isolates for novel mutations conferr...

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Principais autores: Daisuke Hagiwara, Teppei Arai, Hiroki Takahashi, Yoko Kusuya, Akira Watanabe, Katsuhiko Kamei
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2018-10-01
coleção:Emerging Infectious Diseases
Assuntos:
azole resistance
drug resistance
Aspergillus fumigatus
non-cyp51A
HMG-CoA reductase
Hmg1
Acesso em linha:https://wwwnc.cdc.gov/eid/article/24/10/18-0730_article
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