Feasibility of Droplet Digital PCR Analysis of Plasma Cell-Free DNA From Kidney Transplant Patients

Increasing research demonstrates the potential of donor-derived cell-free DNA (dd-cfDNA) as a biomarker for monitoring the health of various solid organ transplants. Several methods have been proposed for cfDNA analysis, including real-time PCR, digital PCR, and next generation sequencing-based appr...

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Autors principals:	Barbara Jerič Kokelj, Maja Štalekar, Sebastian Vencken, David Dobnik, Polona Kogovšek, Matjaž Stanonik, Miha Arnol, Maja Ravnikar
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-10-01
Col·lecció:	Frontiers in Medicine
Matèries:	kidney transplantation droplet digital PCR plasma cell-free DNA minor allele quantification assay evaluation graft health monitoring
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmed.2021.748668/full
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