Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process

Abstract Background Cathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors – cystatins. Cathepsins are crucial to antigen processing during viral and bacterial infections, and as such...

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Autors principals:	Magdalena Bossowska-Nowicka, Matylda B. Mielcarska, Marta Romaniewicz, Monika M. Kaczmarek, Karolina P. Gregorczyk-Zboroch, Justyna Struzik, Marta Grodzik, Małgorzata M. Gieryńska, Felix N. Toka, Lidia Szulc-Dąbrowska
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2019-05-01
Col·lecció:	BMC Microbiology
Matèries:	Cathepsins Cystatins Dendritic cells ECTV
Accés en línia:	http://link.springer.com/article/10.1186/s12866-019-1471-1
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