Cysteamine Eye Drops in Hyaluronic Acid Packaged in Innovative Single-Dose Systems, Part II: Long-Term Stability and Clinical Ocular Biopermanence

Background: Cystinosis is a rare genetic disorder characterized by the accumulation of cystine crystals in several tissues and organs causing, among others, severe eye symptoms. The high instability of cysteamine eye drops makes it difficult to develop formulations with an acceptable shelf life to b...

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Main Authors:	Ana Castro-Balado, Andrea Cuartero-Martínez, Hugo Pena-Verdeal, Gonzalo Hermelo-Vidal, Anja Schmidt, Belén Montero, Manuela Hernández-Blanco, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, María Jesús Giráldez, Eva Yebra-Pimentel, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2023-11-01
Series:	Pharmaceutics
Subjects:	cysteamine cystinosis eye drops ophthalmic administration
Online Access:	https://www.mdpi.com/1999-4923/15/11/2589
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