Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation

This study investigates the role of transient receptor potential ankyrin 1 (TRPA1) in murine temporomandibular joint (TMJ) inflammatory hyperalgesia and the influence of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome. Two distinct murine models of TMJ pain and inflammation (zymosan an...

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Autori principali:	Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan, John Gamble, Yvonne Dombrowski, Paul Moynagh, David Brough, Fionnuala T. Lundy, Susan D. Brain, Ikhlas A. El Karim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-10-01
Serie:	Pharmaceuticals
Soggetti:	temporomandibular arthritis TRPA1 NLRP inflammasome mouse
Accesso online:	https://www.mdpi.com/1424-8247/14/11/1073
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