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Bushen Huatan formula improves reproductive and endocrine metabolic disorders in non-obese polycystic ovary syndrome rats via adipose tissue-derived exosomal miR-27a-3p/PPARG signaling pathway

Objectives This study aims to investigate the therapeutic effects of the Bushen Huatan (BSHT) Formula on non-obese polycystic ovary syndrome (PCOS) rats, and to explore its potential mechanisms of action.Methods A PCOS model was induced in rats via letrozole, a high-fat/high-sucrose diet, and a PEPD...

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Autori principali: Meng Chen, Ruiyuan Zhang, Ying Huang, Yuxin Pan, Jinrong Yang, Yinghong Huang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2026-12-01
Serie:Gynecological Endocrinology
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Accesso online:https://www.tandfonline.com/doi/10.1080/09513590.2026.2655498
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