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Regenerative effect of human cell-derived BMP-2 cultured within a collagen bone graft in a rat calvaria defect model

Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive factor; however, current clinical applications using Escherichia coli -derived recombinant human BMP-2 are constrained by structural deficiencies and high-dose requirements, which increases the risk of adverse effects. In this study, we...

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Huvudupphov: Keun-Suh Kim, Euna Pi, Sang-Jun Park, Seungyoon Lee, Inyoung Choi, Taeuk Kim, Hyo-Jung Lee, Yang-Jin Yi
Materialtyp: Artigo
Språk:Inglês
Utgiven: SAGE Publishing 2025-04-01
Serie:Journal of Applied Biomaterials & Functional Materials
Länkar:https://doi.org/10.1177/22808000251326799
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