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Immunogenicity test of tetanus component in adsorbed vaccines by toxin binding inhibition test

Samples from 20 lots of diphtheria-tetanus (adult use dT) vaccine and from 20 lots of diphtheria-tetanus-pertussis (DTP) vaccine were used to standardize and validate the in vitro toxin binding inhibition (ToBI) test for the immunogenicity test of the tetanus component. The levels of tetanus antitox...

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Principais autores: Denise Cristina Souza Matos, Rugimar Marcovistz, Pedro Hernan Cabello, Ricardo Amaral Georgini, Dirce Sakauchi, Luciana Leite da Silva
Format: Artigo
Sprog:Inglês
Udgivet: Fundação Oswaldo Cruz (FIOCRUZ) 2002-09-01
Serier:Memorias do Instituto Oswaldo Cruz
Fag:
diphtheria-tetanus vaccine
diphtheria-tetanus-pertussis vaccine
toxin binding inhibition test
tetanus
quality control
seroneutralization
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600030
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