Mitochondrial impairment and repair in the pathogenesis of systemic lupus erythematosus

Nucleic acid autoantibodies, increase type I interferon (IFN-α) levels, and immune cell hyperactivation are hallmarks of systemic lupus erythematosus (SLE). Notably, immune cell activation requires high level of cellular energy that is predominately generated by the mitochondria. Mitochondrial react...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Like Zhao, Xianda Hu, Fei Xiao, Xuan Zhang, Lidan Zhao, Min Wang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-07-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	systemic lupus erythematosus mitochondrial reactive oxygen species mitochondrial dysfunction mitophagy oxidative stress mitochondria targeting therapeutics
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.929520/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!