Secretory IgA impacts the microbiota density in the human nose

Abstract Background Respiratory mucosal host defense relies on the production of secretory IgA (sIgA) antibodies, but we currently lack a fundamental understanding of how sIgA is induced by contact with microbes and how such immune responses may vary between humans. Defense of the nasal mucosal barr...

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Bibliographic Details

Main Authors:	Rob van Dalen, Ahmed M. A. Elsherbini, Mareike Harms, Svenja Alber, Regine Stemmler, Andreas Peschel
Format:	Artigo
Language:	Inglês
Published:	BMC 2023-10-01
Series:	Microbiome
Subjects:	Mucosal immunology Secretory IgA IgA-seq Nasal antibodies Nasal microbiota
Online Access:	https://doi.org/10.1186/s40168-023-01675-y
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