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The epithelial Na+ channel UNC-8 promotes an endocytic mechanism that recycles presynaptic components to new boutons in remodeling neurons

Summary: Circuit refinement involves the formation of new presynaptic boutons as others are dismantled. Nascent presynaptic sites can incorporate material from recently eliminated synapses, but the recycling mechanisms remain elusive. In early-stage C. elegans larvae, the presynaptic boutons of GABA...

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Principais autores: Andrea Cuentas-Condori, Siqi Chen, Mia Krout, Kristin L. Gallik, John Tipps, Casey Gailey, Leah Flautt, Hongkyun Kim, Ben Mulcahy, Mei Zhen, Janet E. Richmond, David M. Miller, III
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2023-11-01
Series:Cell Reports
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124723013396
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