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Structural insights into the recruitment of viral type 2 IRES to ribosomal preinitiation complex for protein synthesis

Picornaviruses employ internal ribosome entry sites (IRESs) in their genomic RNA to hijack the host’s translational machinery. The picornavirus, encephalomyocarditis virus, employs a type 2 IRES present in its 5’ untranslated region (5’UTR) and requires 43S ribosomal preinitiation complex (PIC), the...

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Principais autores: Deepakash Das, Tanweer Hussain
格式: Artigo
语言:Inglês
出版: eLife Sciences Publications Ltd 2026-06-01
丛编:eLife
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在线阅读:https://elifesciences.org/articles/107788
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