The Role of Cellular Senescence and SASP in the Pathogenesis of Atherosclerosis and the Therapeutic Potential of Senolytic Strategies in Cardiovascular Diseases

Cellular senescence is a permanent cell cycle arrest that plays a critical role in the development and pathogenesis of age-related diseases. This paper aims to present the biological mechanisms of cellular senescence and the role of the senescence-associated secretory phenotype (SASP) in the pathoge...

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Principais autores:	Zuzanna Krupa, Joanna Wrona, Marta Zawadzka, Julia Rydzek, Julia Lizon, Paulina Kalemba, Konrad Kochman, Paweł Iwaszkiewicz, Robert Iwanowski, Sławomir Woźniak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-01-01
coleção:	Biomedicines
Assuntos:	cellular senescence senescence-associated secretory phenotype (SASP) atherosclerosis cardiovascular diseases senolytics senomorphics
Acesso em linha:	https://www.mdpi.com/2227-9059/14/2/331
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