Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

Prolonged or excessive microglial activation may lead to disturbances in the resolution of inflammation (RoI). The importance of specialized pro-resolving lipid mediators (SPMs) in RoI has been highlighted. Among them, lipoxins (LXA4) and aspirin-triggered lipoxin A4 (AT-LXA4) mediate beneficial res...

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Detaylı Bibliyografya
Asıl Yazarlar:	Kinga Tylek, Ewa Trojan, Monika Leśkiewicz, Magdalena Regulska, Natalia Bryniarska, Katarzyna Curzytek, Enza Lacivita, Marcello Leopoldo, Agnieszka Basta-Kaim
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2021-09-01
Seri Bilgileri:	Cells
Konular:	microglia lipopolysaccharide lipoxin A4 aspirin-triggered lipoxin A4 MR-39 formyl peptide receptor 2
Online Erişim:	https://www.mdpi.com/2073-4409/10/9/2373
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

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