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Uncovering the Link Between Kynurenic Acid Pathway and Kidney Failure

Introduction: Recent studies have focused on some uremic toxins, particularly those derived from tryptophan, as potential modifiable risk factors of chronic kidney disease (CKD) progression. The kynurenine pathway is the major enzymatic pathway for sequentially catabolizing tryptophan, resulting in...

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Principais autores: Carolla El Chamieh, Sophie Liabeuf, Islam Amine Larabi, Natalia Alencar De Pinho, Margaux Costes-Albrespic, Luc Frimat, Céline Lange, Yves-Édouard Herpe, Jean-Charles Martin, Pierre Letourneau, Benoit Bérengère, Christophe Soulage, Stéphane Burtey, Jean-Claude Alvarez, Laetitia Koppe, Ziad A. Massy, Prs T. Hannedouche, B. Moulin, Dr A. Klein, Pr C. Combe, Dr J.P. Bourdenx, Dr A. Keller, Dr C. Delclaux, Dr B. Vendrely, Dr B. Deroure, Dr A. Lacraz, Dr T. Lobbedez, Dr I. Landru, Pr Z. Massy, Pr P. Lang, Dr X. Belenfant, Pr E. Thervet, Dr P. Urena, Dr M. Delahousse, Dr C. Vela, Pr M. Essig, Dr D. Clément, Dr H. Sekhri, Dr M. Smati, Dr M. Jamali, Dr B. Hacq, Dr V. Panescu, Dr M. Bellou, Pr Luc Frimat, Pr N. Kamar, Prs C. Noël et F. Glowacki, Dr N. Maisonneuve, Dr R. Azar, Dr M. Hoffmann, Pr M. Hourmant, Dr A. Testa, Dr D. Besnier, Pr G. Choukroun, Dr G. Lambrey, Pr S. Burtey, Dr G. Lebrun, Dr E. Magnant, Pr M. Laville, Pr D. Fouque, L. Juillard, Dr C. Chazot, Pr P. Zaoui, Dr F. Kuentz
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-05-01
coleção:Kidney International Reports
Assuntos:
chronic kidney disease
kidney failure
kynurenic acid pathway
kynurenine
tryptophan
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2468024925001147
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