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PUMILIO proteins promote colorectal cancer growth via suppressing p21

RNA binding proteins can contribute to colorectal cancer (CRC) initiation and development. Here the authors show that PUMILIO proteins, PUM1 and PUM2 contribute to CRC growth by inhibiting p21 expression.

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Bibliografische gegevens
Hoofdauteurs: Yuanyuan Gong, Zukai Liu, Yihang Yuan, Zhenzhen Yang, Jiawei Zhang, Qin Lu, Wei Wang, Chao Fang, Haifan Lin, Sanhong Liu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2022-03-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-022-29309-1
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