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Metabolic Changes in Patients with Premature Ovarian Insufficiency: Adipose Tissue Focus—A Narrative Review

<b>Background:</b> Estrogen plays a crucial role in adipose tissue homeostasis, influencing fat distribution, lipid metabolism, and insulin sensitivity. Through estrogen receptor (ER) activation, particularly ERα, estradiol (E2) regulates adipogenesis, inhibits adipocyte hypertrophy, and promotes in...

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Principais autores: Miriam Sánchez-García, Kapy León-Wu, Regina de Miguel-Ibáñez, Nitzia López-Juárez, Claudia Ramírez-Rentería, Etual Espinosa-Cárdenas, Ernesto Sosa-Eroza, Manuel R. García-Sáenz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-04-01
Serier:Metabolites
Fag:
primary ovarian insufficiency
estrogens
adipose tissue
lipid metabolism
Online adgang:https://www.mdpi.com/2218-1989/15/4/242
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