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Regulation of CAR and PXR Expression in Health and Disease

Pregnane X receptor (PXR, NR1I2) and constitutive androstane receptor (CAR, NR1I3) are members of the nuclear receptor superfamily that mainly act as ligand-activated transcription factors. Their functions have long been associated with the regulation of drug metabolism and disposition, and it is no...

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Hlavní autoři: Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-10-01
Edice:Cells
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On-line přístup:https://www.mdpi.com/2073-4409/9/11/2395
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