Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APPNL-G-F mouse model of Alzheimer disease following long-term voluntary exercise

Abstract Background An active lifestyle is associated with improved cognitive functions in aged people and may prevent or slow down the progression of various neurodegenerative diseases including Alzheimer’s disease (AD). To investigate these protective effects, male APPNL-G-F mice were exposed to l...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Jogender Mehla, Scott H. Deibel, Hadil Karem, Shakhawat Hossain, Sean G. Lacoursiere, Robert J. Sutherland, Majid H. Mohajerani, Robert J. McDonald
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2022-09-01
سلاسل:	Alzheimer’s Research & Therapy
الموضوعات:	Alzheimer disease APPNL-G-F mice Choline acetyltransferase Cognitive dysfunction Microgliosis Physical exercise
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13195-022-01085-6
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!