Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

<p>Abstract</p> <p>Background</p> <p>Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resistance and glucose intolerance in...

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Autors principals:	Sabatini Mary E, Guo Lankai, Lynch Maureen P, Doyle Joseph O, Lee HoJoon, Rueda Bo R, Styer Aaron K
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2011-05-01
Col·lecció:	Journal of Ovarian Research
Matèries:	polycystic ovarian syndrome metformin hyperinsulinemia oocyte superovulation
Accés en línia:	http://www.ovarianresearch.com/content/4/1/8
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