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Mycobacterium leprae and host immune transcriptomic signatures for reactional states in leprosy

BackgroundMycobacterium leprae transcriptomic and human host immune gene expression signatures that demonstrate a plausible association with type I (T1R) and type II reactions (T2R) aid in early diagnosis, prevention of nerve damage and consequent demyelinating neuropathy in leprosy. The aim of the...

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Uloženo v:
Hlavní autoři: Madhusmita Das, Diana David, Ilse Horo, Anouk Van Hooij, Maria Tió-Coma, Annemieke Geluk, Sundeep Chaitanya Vedithi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-03-01
Edice:Frontiers in Microbiology
Témata:
whole transcriptome microarray
Mycobacterium leprae
type I and type II reactions
gene expression signatures
differential expression
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1113318/full
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