Development of a novel regenerative therapy for malignant bone tumors using an autograft containing tumor inactivated by high hydrostatic pressurization (HHP)

Surgical resection of malignant bone tumors leads to significant defects in the normal surrounding tissues that should be reconstructed to avoid amputation. Our research aimed to inactivate osteosarcoma (OS)-affected bone to obtain autologous bone grafts for bone defect reconstruction using a novel...

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Principais autores:	Yuanjiaozi Li, Yasuhiro Katayama, Ie Nie, Takashi Nakano, Eiichi Sawaragi, Michiharu Sakamoto, Hiroki Yamanaka, Itaru Tsuge, Satoru Demura, Yohei Yamada, Hiroyuki Tsuchiya, Naoki Morimoto
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-03-01
Serija:	Regenerative Therapy
Teme:	High hydrostatic pressurization Osteosarcoma Tumor cells Bone defects Inactivation
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2352320423000123
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